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Jun 24 02 11:30 PM
You may get caught off guard by a trigger here or there but don't panic. The exact same tools, plans and exercies
that you used to carry you throught those first few days of early withdrawal are all still available. Stay calm yet, like a Scout, "Be
Jun 24 02 11:40 PM
Jun 25 02 1:10 AM
Jul 11 02 4:22 AM
Oct 30 02 11:02 PM
Jan 23 05 9:47 PM
Dec 22 05 12:10 AM
Feb 15 06 9:32 PM
Sep 13 06 2:43 PM
Sep 14 06 1:05 AM
"We are what we think. Tell yourself this is hard and it will be. Tell yourself the healing is glorious and it will be.
Fear your craves and they will each be nightmares. Believe that you are more powerful than they are, and you will be. Know with every fiber of your being
that there is no force or circumstances on planet earth (including the death or illness of a friend or loved one) that can ever cause you to put slow death to
your lips again, and you won't! We are what we think! "
That has to be one of the most profound statements ever made on the internet. Thank you so much. I cut and pasted that into my quit reasons.
Free from Nicotine for 4 days, 16 hours, 25 minutes.
Feb 3 07 9:45 PM
Mar 26 07 3:39 PM
Limbic Activation to Cigarette Smoking Cues Independent of Nicotine Withdrawal:
A Perfusion fMRI Study
Neuropsychopharmacology. March 21, 2007 [Epub ahead of print]
Franklin TR, Wang Z, Wang J, Sciortino N, Harper D, Li Y, Ehrman R, Kampman K, O'brien CP, Detre JA, Childress AR. Department of Psychiatry, University
of Pennsylvania, Philadelphia, PA, USA.
Exposure to cigarette smoking cues can trigger physiological arousal and desire to smoke. The brain substrates of smoking cue-induced craving (CIC) are
beginning to be elucidated; however, it has been difficult to study this state independent of the potential contributions of pharmacological withdrawal
from nicotine. Pharmacological withdrawal itself may have substantial effects on brain activation to cues, either by obscuring or enhancing it, and as CIC
is not reduced by nicotine replacement strategies, its neuro-anatomical substrates may differ. Thus, characterizing CIC is critical for developing
This study used arterial spin-labeled (ASL) perfusion fMRI, and newly developed and highly appetitive, explicit smoking stimuli, to examine neural
activity to cigarette CIC in an original experimental design that strongly minimizes contributions from pharmacological withdrawal. Twenty-one smokers (12
females) completed smoking and nonsmoking cue fMRI sessions. Craving self-reports were collected before and after each session. SPM2 software was employed
to analyze data.
Blood flow (perfusion) in a priori-selected regions was greater during exposure to smoking stimuli compared to nonsmoking stimuli (p<0.01; corrected) in
ventral striatum, amygdala, orbitofrontal cortex, hippocampus, medial thalamus, and left insula. Perfusion positively correlated with intensity of
cigarette CIC in both the dorsolateral prefrontal cortex (r(2)=0.54) and posterior cingulate (r(2)=0.53).
This pattern of activation that includes the ventral striatum, a critical reward substrate, and the interconnected amygdala, cingulate and OFC, is
consistent with decades of animal research on the neural correlates of conditioned drug reward.
PMID: 17375140 [PubMed - as supplied by publisher]
Aug 28 10 12:21 PM
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