The following article is from the ALA's web site at the below link and is an excellent basic primer on emphysema. I know that some of our members do have breathing disorders and maybe they shed a bit more light on this important topic. Maybe Joel or one of you can help answer my pretty basic questions. As stated below, emphysema results from the destruction of our alveoloi. The explanations that I keep reading, including this one, make it sound like that except for an extremely small portion of victims who may inherit a specific gene, that the damage to our alveoloi is caused by external substances that enter the lung and eventually lead to permanent damage. My questions are: (1) Is emphysema a true disease in the traditional sense; and, (2) although the alveoli once damaged can't repair themselves, does additional harm and damage immediately cease once we quit smoking? Thanks, Zep
From the American Lung Association
What Is Emphysema?Emphysema is a condition in which there is over-inflation of structures in the lungs known as alveoli or air sacs. This over-inflation results from a breakdown of the walls of the alveoli, which causes a decrease in respiratory function (the way the lungs work) and often, breathlessness.
Early symptoms of emphysema include shortness of breath and cough.
How Serious Is Emphysema?Emphysema is a widespread disease of the lungs. In 1993, 1.9 million people in the U.S. had emphysema.
It is estimated that 50,000 to 100,000 Americans living today were born with a deficiency of a protein known as alpha 1-antitrypsin (AAT) which can lead to an inherited form of emphysema.
Emphysema ranks 15th among chronic conditions that contribute to activity limitations: over 43 percent of individuals with emphysema report that their daily activities have been limited by the disease.
Many of the people with emphysema are older men, but the condition is increasing among women. Males with emphysema outnumber females by 22 percent.
Causes Of EmphysemaThe lung has a system of elastic fibers. The fibers allow the lungs to expand and contract. It is known from scientific research that the normal lung has a remarkable balance between two classes of chemicals with opposing action.
When the chemical balance is altered, the lungs lose the ability to protect themselves against the destruction of these elastic fibers. This is what happens in emphysema.
There are a number of reasons this chemical imbalance occurs. Smoking is responsible for 82 percent of chronic lung disease, including emphysema. Exposure to air pollution is one suspected cause. Irritating fumes and dusts on the job also are thought to be a factor.
A small number of people with emphysema have a rare inherited form of the disease called alpha 1-antitrypsin (AAT) deficiency-related emphysema, or early onset emphysema. This form of disease is caused by an inherited lack of a protective protein called alpha 1-antitrypsin (AAT).
How Does Emphysema Develop?Emphysema begins with the destruction of air sacs (alveoli) in the lungs where oxygen from the air is exchanged for carbon dioxide in the blood. The walls of the air sacs are thin and fragile. Damage to the air sacs is irreversible and results in permanent "holes" in the tissues of the lower lungs.
As air sacs are destroyed, the lungs are able to transfer less and less oxygen to the bloodstream, causing shortness of breath. The lungs also lose their elasticity. The patient experiences great difficulty exhaling.
Emphysema doesn't develop suddenly, it comes on very gradually. Years of exposure to the irritation of cigarette smoke usually precede the development of emphysema.
A person may initially visit the doctor because he or she has begun to feel short of breath during activity or exercise. As the disease progresses, a brief walk can be enough to bring on difficulty in breathing. Some people may have had chronic bronchitis before developing emphysema.
Treatment For Emphysema
- Doctors can help persons with emphysema live more comfortably with their disease. The goal of treatment is to provide relief of symptoms and
prevent progression of the disease with a minimum of side effects. The doctor's advice and treatment may include:
- Quitting smoking: the single most important factor for maintaining healthy lungs.
- Bronchodilator drugs (prescription drugs that relax and open air passages in the lungs): may be prescribed to treat emphysema if there is a tendency toward airway constriction or tightening. These drugs may be inhaled as aerosol sprays or taken orally.
- Antibiotics: if you have a bacterial infection, such as pneumococcal pneumonia.
- Exercise: including breathing exercises to strengthen the muscles used in breathing as part of a pulmonary* rehabilitation program to
condition the rest of the body.
*The term "pulmonary" refers to the lungs.
- Treatment: with Alpha 1-Proteinase Inhibitor (A1PI) only if a person has AAT deficiency-related emphysema. A1PI is not recommended for those who develop emphysema as a result of cigarette smoking or other environmental factors.
- Lung transplantation: most recent reports have been encouraging and the success rate continues to increase.
- Lung reduction surgery: this new technique shows promise. Experience at this time is limited.
Emphysema ResearchContinuing research is being done to find answers to many questions about emphysema, especially about the best ways to prevent the disease.
Researchers know that quitting smoking can prevent the occurrence and decrease the progression of emphysema. Other environmental controls can also help prevent the disease.
- If an individual has emphysema, the doctor will work hard to prevent the disease from getting worse by keeping the patient healthy and clear
of any infection. The patient can participate in this prevention effort by following these general health guidelines:
- Emphysema is a serious disease. It damages your lungs, and it can damage your heart. See your doctor at the first sign of symptoms.
- DON'T SMOKE. A majority of those who get emphysema are smokers. Continued smoking makes emphysema worse, especially for those who have AAT deficiency, the inherited form of emphysema.
- Maintain overall good health habits, which include proper nutrition, adequate sleep, and regular exercise to build up your stamina and resistance to infections.
- Reduce your exposure to air pollution, which may aggravate symptoms of emphysema. Refer to radio or television weather reports or your local newspaper for information about air quality. On days when the ozone (smog) level is unhealthy, restrict your activity to early morning or evening. When pollution levels are dangerous, remain indoors and stay as comfortable as possible.
- Consult your doctor at the start of any cold or respiratory infection because infection can make your emphysema symptoms worse. Ask about getting vaccinated against influenza and pneumococcal pneumonia.
COPD: A Growing ProblemChronic obstructive pulmonary disease (COPD), a term that generally applies to chronic bronchitis and/or emphysema, has increased by a dramatic 57 percent between 1982 and 1993.
Today, chronic bronchitis and emphysema combined constitute the most common chronic lung disease, affecting 15.8 million people in the U.S.
The number of lives claimed by chronic lung disease has increased sharply, too. In 1979, it accounted for about 50,000 deaths. In 1982, the number rose to 59,000 and by 1992, the number of deaths reached 86,974.